B M B Courses
BIOCHEMISTRY AND MOLECULAR BIOLOGY
B M B 001 (GN) Understanding the Bases of Human Disease (3) A broad survey of the molecular and cellular factors that contribute to an understanding of selected human diseases.
B M B 211 Elementary Biochemistry (3) An overview of biochemistry that includes properties of biomolecules, bioenergetics, metabolism, nutrition, genetics, and molecular biology. Prerequisite: CHEM 110;CHEM 202 or CHEM 210
B M B 221 Applied Biochemistry (2) Application and correlation of biochemical events to physiological-nutritional processes in specialized cells, fluids, and whole animals. Students may not receive credit for both B M B 221 and 401. Prerequisite: B M B 211
B M B 251 (MICRB 251) Molecular and Cell Biology I (3) Biomolecules, genetic mechanisms, organization of cells and their organelles, DNA replication, protein synthesis, membranes, the cell nucleus, energy conversion. Prerequisite: CHEM 112
B M B 251H Molecular and Cell Biology I (3) Biomolecules, genetic mechanisms, organization of cells and their organelles, DNA replication, protein synthesis, membranes, the cell nucleus, energy conversion. Prerequisite: CHEM 112
B M B 252 (MICRB 252) Molecular and Cell Biology II (3) Continuation of B M B/MICRB 251; cytoskeleton, cell growth, division, adhesion, signalling, germ cells, differentiation, immune system, nervous system, plant cells. Prerequisite: B M B 251
B M B 252H Molecular and Cell Biology II (3) Continuation of B M B 251H; cytoskeleton, cell growth, division, adhesion, signaling, germ cells, differentiation, immune system, nervous system, plant cells. Prerequisite: B M B 251H
B M B 400 Molecular Biology of the Gene (2-3) Biochemistry of genetic phenomena, including the structure, replication and dynamics of genes and chromosomes, their expression and regulation. Prerequisite: BIOL 222 or BIOL 322;BIOL 230W or B M B 251;CHEM 212
B M B 401 General Biochemistry (3) Principles of the structure and function of biological molecules, including carbohydrates, lipids, membranes, proteins, and enzymes. Students may not receive credit for both CHEM 476 and B M B 401. Prerequisite: CHEM 212;B M B 251 or BIOL 230
B M B 401H General Biochemistry (3) Principles of the structure and function of biological molecules, including carbohydrates, lipids, membranes, proteins, and enzymes. Students may not receive credit for both CHEM 476 and B M B 401H. Prerequisite: CHEM 212;B M B 251 or BIOL 230W
B M B 408 Laboratory Instructional Practice (1-2) Participation in the instruction of undergraduate laboratory and lecture courses, including classroom preparation; discussion of principles and objectives of each exercise. Prerequisite: 10 credits in biochemistry and molecular biology and permission of the department.
B M B 411 Survey of Biochemistry and Molecular Biology Literature (1) An introduction to readings and oral presentations in biochemistry and molecular biology.
Prerequisite: B M B 401;B M B 400 or B M B 402
B M B 428 Physical Chemistry with Biological Applications (3) Chemical thermodynamics and kinetics with applications to biological problems. Prerequisite: CHEM 203 or CHEM 212;PHYS 203 or PHYS 251 ; 3 credits in cell biology
B M B 430 (BIOL 430, ENT 430) Developmental Biology (3) Molecular and genetic analyses of mechanisms involved in differentiation and determination in biological systems.
Prerequisite: BIOL 222;B M B 252 or BIOL 230
B M B 433 (VB SC 433) Molecular and Cellular Toxicology (3) In-depth coverage of processes by which drugs/chemicals interact with biological systems and the experimental approaches used to study these interactions. Prerequisite: B M B 401
B M B 435 (MICRB 435, VB SC 435) Viral Pathogensis (2) A study of the molecular, immunological and pathological aspects of viral diseases as well as laboratory methods of diagnosis. Prerequisite: MICRB 201;B M B 251 and B M B 252 or BIOL 110 and BIOL 230W
B M B 437 Physiological Biochemistry (2) Physiological aspects of biochemistry, with emphasis on mammalian metabolism, specialized tissue and fluid functions, detoxification mechanisms, energetics, and physiological interrelationships. Prerequisite: B M B 402
B M B 442 Laboratory in Proteins, Nucleic Acids, and Molecular Cloning (3) Laboratory in enzyme purification and assay techniques; nucleic acid isolation and characterization, including plasmid preparation. Prerequisite: B M B 251, BIOL 230W or MICRB 201;CHEM 202 or CHEM 210 . Prerequisite or concurrent:B M B 211 or B M B 401
B M B 443W Laboratory in Protein Purification and Enzymology (3) Laboratory in protein isolation methodology, enzyme kinetics, and physico- chemical properties of proteins. Prerequisite: B M B 442, B M B 401
B M B 444 Laboratory in Carbohydrates and Lipids ( ) CARBO LIPIDS LAB (1:0:3)
Laboratory in the isolation, quantification, and characterization of carbohydrates and lipids.
PREREQUISITE: B M B 442, B M B 401
B M B 445W Laboratory in Molecular Genetics I (2) Laboratory in molecular techniques in gene analysis and microbial genetics, emphasizing in vitro methodologies. Prerequisite: B M B 442, B M B 400, MICRB 202
B M B 448 Model Systems and Approaches in Cell Biology Inquiry (2) Advanced laboratory that uses inquiry-based approaches to the analysis of organelles, genetic mechanisms, and metabolic processes in eukaryotic organisms. Prerequisite: MICRB 202, B M B 442 or MICRB 442 and B M B 251 or MICRB 251 or BIOL 230
B M B 450 (MICRB 450) Microbial/Molecular Genetics (2) Genetic phenomena, with emphasis on molecular mechanisms: gene transfer, recombination, gene conversion, gene fusion, suppression, transposons. Prerequisite: BIOL 222 or BIOL 322, MICRB 201
B M B 460 (MICRB 460) Cell Growth and Differentiation (3) Mechanisms and regulation of protein trafficking, organelle biosynthesis, cell development, signaling and cell cycle control. Emphasizes experimental design and analysis. Prerequisite: B M B 252
B M B 474 Analytical Biochemistry (3) Physical/chemical theory and techniques that emphasize purification and characterization of biological macromolecules, including proteins, lipids and nucleic acids. Prerequisite: Prerequisite or concurrent:B M B 428 or CHEM 450
B M B 480 (MICRB 480) Tumor Viruses and Oncogenes (3) Oncogenes, DNA and RNA tumor viruses, and relevant experimental techniques with emphasis on molecular basis of carcinogenesis and gene regulation. Prerequisite: or concurrent:MICRB 415, MICRB 435 or MICRB 460
B M B 482 (497F) Informational Bioinformatics (3) Introduction to the biological problems and computational solutions that motivate current applications in computational biology. Topics will be organized around three main themes: 1) Genomes, including assembly and annotation of genomic sequences; 2) Evolution, including sequence comparison, reconstruction of evolutionary relationships, and detection of disease associated traits; and 3) Function, including analysis of functional genomics experiments and characterization of regulatory relationships between genes. Prerequisite: B M B/MICRB 251.
B M B 484 (497B) Functional Genomics (3) An Exploration of biochemical, genetic, and evolutionary approaches to comprehensive discovery of functional DNA segments in genomes, including genes (those encoding proteins and those producing noncoding transcripts) and the DNA sequences needed for regulating their expression (promoters, enhancers, silencers, etc.). Examples may be drawn from the genome of any species, but most will focus on the genomes of mammals, especially humans and mouse. Students will work with genomic and epigenomic data using web-based tools, and will develop projects (research or educational) illuminating important topics in functional genomics.
B M B 485 (498D) Human Genomics and Biomedical Informatics (3) Introduction to molecular, statistical, population, and analytical aspects of modern human genomics and biomedical informatics; genetic architecture of complex diseases.Prerequisite: BIOL 322, B M B 400 and STAT 301 or STAT 401
B M B 488 Communities of Practice in Biochemistry and Molecular Biology (2 per semester/ maximum of 16) The course combines laboratory research in a community of practice and a seminar on topics in science, ethics, and society. Prerequisite: MICRB 202
- Section 001: Antibiotics: Development and Resistance
- Section 002: Gene Organogenesis
- Section 003: Genetics and genomics: principles and practice
- Section 004: Gene Regulation
- Section 005: RNA Biology
- Section 006: Host-Microbe Interactions
B M B 496 Independent Studies (1-18) Creative projects, including research and design, which are supervised on an individual basis and which fall outside the scope of formal courses.
B M B 497 Special Topics (1-9) Formal courses given infrequently to explore, in depth, a comparatively narrow subject which may be topical or of special interest.
Effective: Spring 1995
B M B 497A Practical Applications of Enzymology (2) Focus on understanding enzymes and enzyme activity well enough to deal with their use in real-world situations.
B M B 497G Bioremediation and Green Chemistry (3) Application of biological and engineering principles toward remediation of hazardous wastes and synthesis of chemicals in a sustainable manner. Emphasis on metabolic engineering systems biology, and protein engineering to accomplish these aims. Biological contacting devices for waste remediation. Prerequisite: CHEM 212; B M B 251 or MICRB 201
B M B 498 Special Topics (1-9) Formal courses given infrequently to explore, in depth, a comparatively narrow subject that may be topical or of special interest.
B M B 498D Human Genomics and Biomedical Informatics (3) Introduction to molecular, statistical, population, and analytical aspects of modern human genomics and biomedical informatics; genetic architecture of complex diseases. Prerequisite: BIOL 322, B M B 400 and STAT 301 or STAT 401