B M B Courses

• Online Course Syllabi
  

BIOCHEMISTRY AND MOLECULAR BIOLOGY

B M B 001 (GN) Understanding the Bases of Human Disease (3) A broad survey of the molecular and cellular factors that contribute to an understanding of selected human diseases. 

B M B 211 Elementary Biochemistry (3) An overview of biochemistry that includes properties of biomolecules, bioenergetics, metabolism, nutrition, genetics, and molecular biology.   Prerequisite: CHEM 110;CHEM 202 or CHEM 210  

B M B 212 Elementary Biochemistry Laboratory (1) Selected experiments to illustrate major biochemical principles and techniques. Prerequisite: or concurrent:B M B 211  

B M B 221 Applied Biochemistry (2) Application and correlation of biochemical events to physiological-nutritional processes in specialized cells, fluids, and whole animals. Students may not receive credit for both B M B 221 and 401. Prerequisite: B M B 211  

B M B 251 (MICRB 251) Molecular and Cell Biology I (3) Biomolecules, genetic mechanisms, organization of cells and their organelles, DNA replication, protein synthesis, membranes, the cell nucleus, energy conversion. Prerequisite: CHEM 112  

B M B 251H Molecular and Cell Biology I (3) Biomolecules, genetic mechanisms, organization of cells and their organelles, DNA replication, protein synthesis, membranes, the cell nucleus, energy conversion. Prerequisite: CHEM 112  

B M B 252 (MICRB 252) Molecular and Cell Biology II (3) Continuation of B M B/MICRB 251; cytoskeleton, cell growth, division, adhesion, signalling, germ cells, differentiation, immune system, nervous system, plant cells. Prerequisite: B M B 251  

B M B 252H Molecular and Cell Biology II (3) Continuation of B M B 251H; cytoskeleton, cell growth, division, adhesion, signaling, germ cells, differentiation, immune system, nervous system, plant cells. Prerequisite: B M B 251H  

B M B 400 Molecular Biology of the Gene (2-3) Biochemistry of genetic phenomena, including the structure, replication and dynamics of genes and chromosomes, their expression and regulation. Prerequisite: BIOL 222 or BIOL 322;BIOL 230W or B M B 251;CHEM 212  

B M B 401 General Biochemistry (3) Principles of the structure and function of biological molecules, including carbohydrates, lipids, membranes, proteins, and enzymes. Students may not receive credit for both CHEM 476 and B M B 401. Prerequisite: CHEM 212;B M B 251 or BIOL 230  

B M B 401H General Biochemistry (3) Principles of the structure and function of biological molecules, including carbohydrates, lipids, membranes, proteins, and enzymes. Students may not receive credit for both CHEM 476 and B M B 401H. Prerequisite: CHEM 212;B M B 251 or BIOL 230W  

B M B 402 General Biochemistry (3) Comprehensive survey of the pathways and regulation of intermediary metabolism. Prerequisite: B M B 401 or CHEM 476  

B M B 402H General Biochemistry (3) Comprehensive survey of the pathways and regulation of intermediary metabolism. Prerequisite: B M B 401H  

B M B 408 Laboratory Instructional Practice (1-2) Participation in the instruction of undergraduate laboratory courses, including classroom preparation; discussion of principles and objectives of each exercise. Prerequisite: 10 credits in biochemistry and molecular biology and permission of the department  

B M B 411 Survey of Biochemistry and Molecular Biology Literature (1) An introduction to readings and oral presentations in biochemistry and molecular biology.
Prerequisite: B M B 401;B M B 400 or B M B 402  

B M B 428 Physical Chemistry with Biological Applications (3) Chemical thermodynamics and kinetics with applications to biological problems. Prerequisite: CHEM 203 or CHEM 212;PHYS 203 or PHYS 251 ; 3 credits in cell biology  

B M B 430 (BIOL 430, ENT 430) Developmental Biology (3) Molecular and genetic analyses of mechanisms involved in differentiation and determination in biological systems.
Prerequisite: BIOL 222;B M B 252 or BIOL 230  

B M B 432 (MICRB 432, VB SC 432) Advanced Immunology: Signaling in the Immune System (3) The study of signaling pathways that regulate the immune response.
Prerequisite: B M B 400, MICRB 410  

B M B 433 (VB SC 433) Molecular and Cellular Toxicology (3) In-depth coverage of processes by which drugs/chemicals interact with biological systems and the experimental approaches used to study these interactions. Prerequisite: B M B 401  

B M B 435 (MICRB 435, VB SC 435) Viral Pathogensis (2) A study of the molecular, immunological and pathological aspects of viral diseases as well as laboratory methods of diagnosis. Prerequisite: MICRB 201;B M B 251 and B M B 252 or BIOL 110 and BIOL 230W

B M B 437 Physiological Biochemistry (2) Physiological aspects of biochemistry, with emphasis on mammalian metabolism, specialized tissue and fluid functions, detoxification mechanisms, energetics, and physiological interrelationships. Prerequisite: B M B 402  

B M B 442 (MICRB 442) Laboratory in Proteins, Nucleic Acids, and Molecular Cloning (3) Laboratory in enzyme purifications and assay techniques; nucleic acid isolation and characterization, including plasmid preparation. Prerequisite: B M B 251, BIOL 230W or MICRB 201;CHEM 202 or CHEM 210 . Prerequisite or concurrent:B M B 211 or B M B 401  

B M B 443W Laboratory in Protein Purification and Enzymology (3) Laboratory in protein isolation methodology, enzyme kinetics, and physico- chemical properties of proteins. Prerequisite: B M B 442, B M B 401  

B M B 445W Laboratory in Molecular Genetics I (2) Laboratory in molecular techniques in gene analysis and microbial genetics, emphasizing in vitro methodologies. Prerequisite: B M B 442, B M B 400, MICRB 202  

B M B 446 Laboratory in Molecular Genetics II (1) Laboratory in gene analysis and microbial genetics, emphasizing in vivo methodologies. Prerequisite: B M B 442, B M B 400, MICRB 202  

B M B 450 (MICRB 450) Microbial/Molecular Genetics (2) Genetic phenomena, with emphasis on molecular mechanisms: gene transfer, recombination, gene conversion, gene fusion, suppression, transposons. Prerequisite: BIOL 222 or BIOL 322, MICRB 201  

B M B 460 (MICRB 460) Cell Growth and Differentiation (3) Mechanisms and regulation of protein trafficking, organelle biosynthesis, cell development, signaling and cell cycle control. Emphasizes experimental design and analysis. Prerequisite: B M B 252  

B M B 464 Molecular Medicine (3) An exploration of the impact of advances in molecular biology on understanding disease mechanisms, medical diagnosis, and therapeutics. Prerequisite: B M B 251  

B M B 474 Analytical Biochemistry (3) Physical/chemical theory and techniques that emphasize purification and characterization of biological macromolecules, including proteins, lipids and nucleic acids. Prerequisite: Prerequisite or concurrent:B M B 428 or CHEM 450  

B M B 480 (MICRB 480) Tumor Viruses and Oncogenes (3) Oncogenes, DNA and RNA tumor viruses, and relevant experimental techniques with emphasis on molecular basis of carcinogenesis and gene regulation. Prerequisite: or concurrent:MICRB 415, MICRB 435 or MICRB 460  

B M B 496 Independent Studies (1-18) Creative projects, including research and design, which are supervised on an individual basis and which fall outside the scope of formal courses. 

B M B 497 Special Topics (1-9) Formal courses given infrequently to explore, in depth, a comparatively narrow subject which may be topical or of special interest.
Effective: Spring 1995 

B M B 497A Practical Applications of Enzymology (1) Focus on understanding enzymes and enzyme activity well enough to deal with their use in real-world situations. 

B M B 497B Functional Genomics (3) An Exploration of biochemical, genetic, and evolutionary approaches to comprehensive discovery of functional DNA segments in genomes, including genes (those encoding proteins and those producing noncoding transcripts) and the DNA sequences needed for regulating their expression (promoters, enhancers, silencers, etc.). Examples may be drawn from the genome of any species, but most will focus on the genomes of mammals, especially humans and mouse. Students will work with genomic and epigenomic data using web-based tools, and will develop projects (research or educational) illuminating important topics in functional genomics.

B M B 497C Metals in Biology (1) Formal courses given infrequently to explore, in depth, a comparatively narrow subject which may be topical or of special interest. 

B M B 498 Special Topics (1-9) Formal courses given infrequently to explore, in depth, a comparatively narrow subject that may be topical or of special interest. 

B M B 498A (MICRB 498A) Antibiotics: Development and Resistance (2) Formal courses given infrequently to explore, in depth, a comparatively narrow subject that may be topical or of special interest. 

B M B 498A (MICRB 498A) Antibiotics: Development and Resistance (2) Formal courses given infrequently to explore, in depth, a comparatively narrow subject that may be topical or of special interest. 

B M B 498B Cell Biology Methods (2) Advanced laboratory in the visualization and analysis of organelles, genetic mechanisms, and metabolic processes in eukaryotes. Prerequisite: MICRB 202, MICRB 252, MICRB 442