Biochemistry and Molecular Biology
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B M B 488 Communities of Practice in Biochemistry and Molecular Biology (2 per semester/maximum of 16) combines laboratory research in a community of practice and a seminar on topics in science, ethics, and society.

Communities of Practice:  B M B 488

B M B 488 Communities of Practice in Biochemistry and Molecular Biology

Section 001:  Antibiotics: Development and Resistance

Is a section that integrates primary research in antibiotic discovery with a student-driven seminar investigating scientific, societal, and ethical issues associated with antibiotic development and the spread of antibiotic resistance. Participation in section 001 of B M B 488 is application based.  Applications are taken the start of every semester.  Instructor approval is required for enrollment in this section.

Hear what a student says about this section experience:

 

Section 002:  Genetic Control of Organogenesis

The goal of section 002 of B M B 488 is to provide authentic research experiences to students who are entering the major and to engage students in a community of practice, a group of scientists with varying levels of experience working toward a shared scientific objective. The scientific objective is to identify genes that direct morphogenesis of biological tubes by using RNAi and DIC microscopy to screen a selection of candidate genes for those with defects in morphogenesis of the C. elegans vulva.  Applications are taken the start of every semester.  Instructor approval is required for enrollment in this section.

 

Section 003: Genetics and genomics: principles and practice

Is a section that integrates primary research in genetics and genomics with a student-driven seminar investigating scientific, societal, and ethical issues associated with gene discovery and the molecular genetic basis of human diseases.  Applications are taken the start of every semester.  Instructor approval is required for enrollment in this section.

 

Section 004:  Gene Regulation

“B M B 488 section 004 will enhance laboratory research experience with a community of practice in the Penn State Center for Eukaryotic Gene Regulation.  Participants will perform gene regulation research in the laboratory of Frank Pugh, Joseph Reese, Song Tan, Yanming Wang, David Gilmour, Lu Bai and Shaun Mahony and participate in weekly student-driven seminars investigating scientific, societal and ethical issues associated with gene regulation and the molecular basis of human diseases.”  Instructor approval is required for enrollment in this section.

 

Section 005:  Communities of Practice: RNA Biology

This section aims to provide participants with a comprehensive introduction to independent research in the field of RNA biology. Students will engage in guided lab projects hosted by the laboratories of Drs. Babitzke, Bevilacqua, Krasilnikov and Murakami. The weekly seminar portion will consist of lectures centered round an RNA biology theme, in addition to providing students with training in essential components of working effectively in a research laboratory.  Instructor approval is required for enrollment in this section.

 

Section 006:  Host-Microbe Interactions

This section of BMB 488 will focus upon how various microbes (bacteria, parasites) can interface with their host, in both pathogenic and beneficial ways. We will discuss how these interactions work, and what their outcomes are for the organism on both sides of the interaction. We will accomplish this through group discussions and presentations of these topics as concepts, but we will also investigate Host-Microbe Interactions by performing original research in the laboratory. Research will be hosted by the laboratories of Drs. Manuel Llinas, and Tim Miyashiro, and will focus on interactions that are new, relevant, and exciting for this field.  Instructor approval is required for enrollment in this section.