Biochemistry and Molecular Biology
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Thomas M. Bodenstine, Ph.D.

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Thomas BodenstineI graduated from the Biotechnology program in 2004. Following graduation, I completed my Ph.D. in Molecular and Cellular Pathology at the University of Alabama at Birmingham where I was a Department of Defense Breast Cancer Research Program Predoctoral Fellow.

I am currently a Postdoctoral Research Associate at Northwestern University training in the National Cancer Institute funded Oncogenesis and Developmental Biology program, performing research in the field of breast cancer metastasis. I am also currently serving on the Associate Member Council of the American Association for Cancer Research.

During my time in the BMB Department at Penn State I received fundamental training, both in the classroom and laboratory, while also developing my technical writing, critical thinking, and research presentation skills. Collectively, this set a solid foundation for me to succeed in later states of my career.

As a Biotechnology major, I completed two cooperative education rotations at GlaxoSmithKline Pharmaceuticals, studying the molecular mechanisms of antimicrobial compounds and at the Children's Hospital of Philadelphia researching reverse cholesterol efflux from macrophages. The diverse research experiences I gained through this training allowed me to apply aspects of molecular biology and protein biochemistry early on in my undergraduate career. This later had a profound impact when I began graduate school by providing me with advanced technical expertise in the biological sciences. Through these unique hands-on research experiences that the Biotechnology program provided, I developed an enthusiasm for biomedical studies and decided to pursue a career in cancer research.

The faculty within the BMB Department at Penn State, specifically my former advisor Dr. Philip Mohr, were incredibly helpful in guiding my path not only during my time as an undergraduate, but also in preparing me for my future career plans. Additionally, Dr. Andrea Mastro provided continued mentorship during my graduate school work and served as a member of my Ph.D. thesis committee and remains a friend and colleague today, continuing to offer research and career advice. 

The relationships I formed with the faculty members in the BMB Department have been long standing and help to highlight the incredibly supportive environment the BMB Department offers to incoming students in the context of academic and professional development.

Selected Publications

Bodenstine TM, Vaidya KS, Ismail A, Beck BH, Cook LM, Diers AR, Landar A, Welch DR. Homotypic gap junctional intercellular communication increases with Protein Kinase A activity and is independent of phosphoinositide-3-kinase inhibition. Cancer Research 2010; 70(23): 10002-10011.

Bodenstine TM, Welch DR. Metastasis Suppressors and the Tumor Microenvironment. Cancer Microenvironment 2008: 1:1-11.